Linking Metabolism to Membrane Signaling: The GABA-Malate Connection.

  title={Linking Metabolism to Membrane Signaling: The GABA-Malate Connection.},
  author={Matthew Gilliham and Stephen D Tyerman},
  journal={Trends in plant science},
  volume={21 4},
γ-Aminobutyric acid (GABA) concentration increases rapidly in tissues when plants encounter abiotic or biotic stress, and GABA manipulation affects growth. This, coupled to GABA's well-described role as a neurotransmitter in mammals, led to over a decade of speculation that GABA is a signal in plants. The discovery of GABA-regulated anion channels in plants provides compelling mechanistic proof that GABA is a legitimate plant-signaling molecule. Here we examine research avenues unlocked by this… CONTINUE READING
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