Linking Colorectal Cancer to Wnt Signaling

  title={Linking Colorectal Cancer to Wnt Signaling},
  author={Mariann Bienz and Hans Clevers},
emerged shortly after this, when the Wnt pathway was *MRC Laboratory of Molecular Biology discovered by genetic analysis in Drosophila. Specific Hills Road mutant phenotypes led to the identification of critical Cambridge CB2 2QH Wnt signaling components, while epistasis experiments United Kingdom determined the functional order of these components ‡Department of Immunology and in the pathway. This established that Armadillo, the fly Center for Biomedical Genetics homolog of b-catenin, mediates… CONTINUE READING
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