Linked color imaging enhances gastric cancer in gastric intestinal metaplasia.
Gastric cancer is the fifth most common cause of cancer-related mortality in the world . Despite advances in chemotherapy, the overall survival of patients with gastric cancer remains poor. To improve the prognosis, detection at an early stage is necessary . Screening esophagogastroduodenoscopy is an effective examination for the early detection of gastric cancer [3–5]. Early gastric cancer involves only slight morphological findings and color differences in relation to the surrounding mucosa. As the difference is subtle, it is difficult for physicians who are unfamiliar with the diagnosis of early gastric cancer and even expert endoscopists to detect it [6, 7]. Linked color imaging (LCI), a novel image-enhanced endoscopy technology, emphasizes the color of early gastric cancer