Linkage of bipolar disorder to chromosome 18q and the validity of bipolar II disorder.

@article{McMahon2001LinkageOB,
  title={Linkage of bipolar disorder to chromosome 18q and the validity of bipolar II disorder.},
  author={Francis J. McMahon and Sylvia G Simpson and Melvin G. McInnis and Judith A. Badner and Dean F Mackinnon and J Raymond Depaulo},
  journal={Archives of general psychiatry},
  year={2001},
  volume={58 11},
  pages={1025-31}
}
BACKGROUND An analysis of the relationship between clinical features and allele sharing could clarify the issue of genetic linkage between bipolar affective disorder (BPAD) and chromosome 18q, contributing to the definition of genetically valid clinical subtypes. METHODS Relatives ascertained through a proband who had bipolar I disorder (BPI) were interviewed by a psychiatrist, assigned an all-sources diagnosis, and genotyped with 32 markers on 18q21-23. Exploratory findings from the first 28… CONTINUE READING

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