Linkage of a microsatellite marker to the canine copper toxicosis locus in Bedlington terriers.

@article{YuzbasiyanGurkan1997LinkageOA,
  title={Linkage of a microsatellite marker to the canine copper toxicosis locus in Bedlington terriers.},
  author={Vilma Yuzbasiyan-Gurkan and Susan Halloran Blanton and Yu-fen Cao and Polly Ferguson and Jianjun Li and Patrick J. Venta and George J. Brewer},
  journal={American journal of veterinary research},
  year={1997},
  volume={58 1},
  pages={23-7}
}
OBJECTIVE To identify a DNA marker for the copper toxicosis (CT) locus in Bedlington Terriers (BT). ANIMALS 77 BT, of which 25 were affected. Diagnosis of affected or unaffected with CT was made in all cases by quantitative copper determinations on liver biopsy samples by use of established criteria. PROCEDURE BT pedigrees segregating for CT were identified. Linkage studies were carried out using polymorphic microsatellite markers developed for the canine genome in these pedigrees. DNA was… CONTINUE READING