Linkage of Marie-Unna hypotrichosis locus to chromosome 8p21 and exclusion of 10 genes including the hairless gene by mutation analysis

@article{Lefevre2000LinkageOM,
  title={Linkage of Marie-Unna hypotrichosis locus to chromosome 8p21 and exclusion of 10 genes including the hairless gene by mutation analysis},
  author={Pascal Ibrahim Lefevre and Ariane Rochat and Christine Bodemer and Pierre Vabres and Yann Barrandon and Yves de Prost and Chad Garner and Alain Hovnanian},
  journal={European Journal of Human Genetics},
  year={2000},
  volume={8},
  pages={273-279}
}
Marie-Unna hypotrichosis (MU) is a rare autosomal dominant congenital alopecia characterised by progressive hair loss starting in early childhood, often aggravated at puberty and leading to scarring alopecia of variable severity. We have studied three multigeneration families of Belgian, British and French descent. The human genome was screened with microsatellite markers spaced at 10-cM intervals and significant evidence for linkage to the disease was observed on chromosome 8p21, with a… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

Genetics of Structural Hair Disorders.

  • The Journal of investigative dermatology
  • 2012
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 34 REFERENCES

Über hypotrichosis congenital hereditaria

M Unna
  • Dermatol Wochenschr
  • 1925
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL