Linkage of Bardet–Biedl syndrome to chromosome 16q and evidence for non–allelic genetic heterogeneity

@article{KwitekBlack1993LinkageOB,
  title={Linkage of Bardet–Biedl syndrome to chromosome 16q and evidence for non–allelic genetic heterogeneity},
  author={Anne E. Kwitek-Black and Rivka Carmi and Geoffrey M. Duyk and Kenneth H. Buetow and Khalil Elbedour and Ruti Parvari and Chandra Naidu Yandava and Edwin M. Stone and Val C. Sheffield},
  journal={Nature Genetics},
  year={1993},
  volume={5},
  pages={392-396}
}
Bardet–Biedl syndrome is an autosomal recessive disorder characterized by mental retardation, obesity, retinitis pigmentosa, polydactyly and hypogonadism. Other findings include hypertension, diabetes mellitus and renal and cardiovascular anomalies. We have performed a genome–wide search for linkage in a large inbred Bedouin family. Pairwise analysis… CONTINUE READING