Linkage mapping of benign familial infantile convulsions (BFIC) to chromosome 19q.

  title={Linkage mapping of benign familial infantile convulsions (BFIC) to chromosome 19q.},
  author={Michel Guipponi and François Rivier and Federico Vigevano and Corinne Beck and Arielle Crespel and Bernard Echenne and Paolo Lucchini and R. Sebastianelli and Michel Baldy-Moulinier and Alain Malafosse},
  journal={Human molecular genetics},
  volume={6 3},
Benign familial infantile convulsions (BFIC) are an autosomal-dominant epileptic syndrome characterized by an age of onset within the first year of life. Although they were first reported in families of Italian descent, BFIC have also been described in non-Italian families. We have mapped the BFIC gene to chromosome 19 by linkage analysis in five Italian families with a maximum two-point lod score of 6.36 at D19S114; maximum multipoint lod scores > 8 were obtained for the interval D19S250… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 43 extracted citations

Benign pediatric localization-related epilepsies. Part I. Syndromes in infancy.

Epileptic disorders : international epilepsy journal with videotape • 2006
View 4 Excerpts
Highly Influenced

Association of a synonymous SCN1B variant affecting splicing efficiency with Benign Familial Infantile Epilepsy (BFIE).

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society • 2017

Similar Papers

Loading similar papers…