Linkage mapping of CVD risk traits in the isolated Norfolk Island population

@article{Bellis2008LinkageMO,
  title={Linkage mapping of CVD risk traits in the isolated Norfolk Island population},
  author={Claire Bellis and Hannah C. Cox and Thomas D. Dyer and Jac C Charlesworth and Kimberly Begley and Sharon K Quinlan and Rod A. Lea and S. C. Heath and John Blangero and Lyn R Griffiths},
  journal={Human Genetics},
  year={2008},
  volume={124},
  pages={543-552}
}
To understand the underlying genetic architecture of cardiovascular disease (CVD) risk traits, we undertook a genome-wide linkage scan to identify CVD quantitative trait loci (QTLs) in 377 individuals from the Norfolk Island population. The central aim of this research focused on the utilization of a genetically and geographically isolated population of individuals from Norfolk Island for the purposes of variance component linkage analysis to identify QTLs involved in CVD risk traits… CONTINUE READING