Linkage disequilibrium in humans: models and data.

  title={Linkage disequilibrium in humans: models and data.},
  author={Jonathan K. Pritchard and Molly Przeworski},
  journal={American journal of human genetics},
  volume={69 1},
In this review, we describe recent empirical and theoretical work on the extent of linkage disequilibrium (LD) in the human genome, comparing the predictions of simple population-genetic models to available data. Several studies report significant LD over distances longer than those predicted by standard models, whereas some data from short, intergenic regions show less LD than would be expected. The apparent discrepancies between theory and data present a challenge-both to modelers and to… CONTINUE READING
Highly Influential
This paper has highly influenced 43 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Figures, tables, and topics from this paper.
517 Citations
71 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 517 extracted citations


Publications referenced by this paper.
Showing 1-10 of 71 references

Principles of population genetics

  • DL Hartl, AG Clark
  • Sinauer Associates,
  • 1997
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…