Linkage disequilibrium in growing and stable populations.

@article{Slatkin1994LinkageDI,
  title={Linkage disequilibrium in growing and stable populations.},
  author={Montgomery Slatkin},
  journal={Genetics},
  year={1994},
  volume={137 1},
  pages={331-6}
}
Nonrandom associations between alleles at different loci can be tested for using Fisher's exact test. Extensive simulations show that there is a substantial probability of obtaining significant nonrandom associations between closely or completely linked polymorphic neutral loci in a population of constant size at equilibrium under mutation and genetic drift. In a rapidly growing population, however, there will be little chance of finding significant nonrandom associations even between… CONTINUE READING
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