Linkage disequilibrium between the MBP tetranucleotide repeat and multiple sclerosis is restricted to a geographically defined subpopulation in Finland

Abstract

We have previously found evidence for linkage as well as allelic and haplotype association between the myelin basic protein (MBP) gene and multiple sclerosis (MS). These findings have, however, not been reproduced in other populations. Here, we have analyzed association between MBP and MS in a new set of 349 Finnish triad families. Families with a parent… (More)
DOI: 10.1038/sj.gene.6363943

Topics

8 Figures and Tables

Cite this paper

@article{Pihlaja2003LinkageDB, title={Linkage disequilibrium between the MBP tetranucleotide repeat and multiple sclerosis is restricted to a geographically defined subpopulation in Finland}, author={Hannele Pihlaja and Terhi Rantam{\"a}ki and Juhani Wikstr{\"{o}m and M L Sumelahti and Mikko I Laaksonen and Jorma Ilonen and Juhani Ruutiainen and Tuula A Pirttil{\"a} and Irina Elovaara and Mauri Reunanen and Satu M Kuokkanen and L. Peltonen and Keijo Koivisto and Pentti J. Tienari}, journal={Genes and Immunity}, year={2003}, volume={4}, pages={138-146} }