Linkage disequilibrium between TNF-α-308 G/A promoter and histocompatibility leukocyte antigen alleles in Han-nationality lung transplant recipients from Eastern China.

@article{Huijun2013LinkageDB,
  title={Linkage disequilibrium between TNF-α-308 G/A promoter and histocompatibility leukocyte antigen alleles in Han-nationality lung transplant recipients from Eastern China.},
  author={Mu Huijun and Zhang Ji and Xie Ping and Chen Jingyu and Zhang Bin},
  journal={Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation},
  year={2013},
  volume={11 3},
  pages={264-9}
}
OBJECTIVES Genes encoding histocompatibility leukocyte antigen (HLA) and proinflammatory cytokines are involved in rejection after organ transplant. The authors explored the association between HLA alleles and the tumor necrosis factor (TNF)- α-308 G/A promoter region in lung transplant recipients of Han nationality from East China. They also evaluated the correlation between TNF-α-308 G/A and the onset of acute rejection after lung transplant. MATERIALS AND METHODS All lung transplant… CONTINUE READING