Linkage disequilibrium and haplotype analysis among four novel single-nucleotide polymorphisms in the human leukemia inhibitory factor (LIF) gene

@article{Ishida2001LinkageDA,
  title={Linkage disequilibrium and haplotype analysis among four novel single-nucleotide polymorphisms in the human leukemia inhibitory factor (LIF) gene},
  author={Ryota Ishida and Yoichi Ezura and Hironori Iwasaki and Ichiro Nakazawa and Mitsuko Kajita and Mina Kodaira and Hiromoto Ito and Mitsuru Emi},
  journal={Journal of Human Genetics},
  year={2001},
  volume={46},
  pages={557-559}
}
AbstractLeukemia inhibitory factor (LIF) is a pleiotropic cytokine implicated in various pathological conditions, such as rheumatoid arthritis and osteoporosis. Despite the possible importance of LIF as a therapeutic target, little is known about the bioregulation of the human LIF gene. We here sequenced the entire structure of the LIF gene of 48 alleles in the Japanese population. These experiments identified four single-nucleotide polymorphisms (SNPs) and determined their allelic frequencies… CONTINUE READING
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