Linkage between androgen receptor gene CAG trinucleotide repeat length and testicular germ cell cancer histological type and clinical stage.

@article{Giwercman2004LinkageBA,
  title={Linkage between androgen receptor gene CAG trinucleotide repeat length and testicular germ cell cancer histological type and clinical stage.},
  author={A Giwercman and Kristina B Lundin and Jakob Eberhard and Olof St{\aa}hl and Magdalena Cwikiel and Eva K Cavallin-St{\aa}hl and Yvonne Lundberg Giwercman},
  journal={European journal of cancer},
  year={2004},
  volume={40 14},
  pages={2152-8}
}
Sex hormones and/or gonadotropins may play a crucial role in the development of testicular germ cell cancer (TGCC). A direct link between this malignancy and endocrine factors has not been confirmed. We tested whether CAG and GGN repeats of the androgen receptor gene (AR) play a role in the aetiology or pathogenesis of TGCC. Eighty-three TGCC patients and 220 controls were included. Mean CAG or GGN lengths did not differ between the TGCC cases and controls. The proportion of males with CAG… CONTINUE READING

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