Link between immune response and parasite synchronization in malaria.

  title={Link between immune response and parasite synchronization in malaria.},
  author={Igor M. Rouzine and F. Ellis McKenzie},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={100 6},
Anti-malaria vaccines and drugs could be greatly improved if we knew which phases of Plasmodium falciparum development in red blood cells are major inducers and which are major targets of natural immune responses. This information should focus attention on relevant immunogens and prove useful in developing immune-based therapies. Here we explore the hypothesis that innate immune responses mediate synchronization between the replication cycles of parasites in different red blood cells which is… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 19 extracted citations

Periodicity and synchronization in blood-stage malaria infection.

Journal of mathematical biology • 2011
View 5 Excerpts
Highly Influenced

The within-host dynamics of malaria infection with immune response.

Mathematical biosciences and engineering : MBE • 2011
View 5 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-4 of 4 references

Malaria (Churchill Livingstone, Edinburgh)

W. H. Wernsdorfer, I. McGregor
View 1 Excerpt

The Primate Malarias (U.S. Department of Health, Education, and Welfare, Bethesda, MD)

G. R. Coatney, W. E. Collins, M. Warren, P. G. Contacos

Malariology (Saunders, Philadelphia)

M. F. Boyd
View 1 Excerpt

Similar Papers

Loading similar papers…