Lingual thyroid and hyperthyroidism: a new case and review of the literature.

  title={Lingual thyroid and hyperthyroidism: a new case and review of the literature.},
  author={M P Abdallah-Matta and P H Dubarry and J J Pessey and Philippe Caron},
  journal={Journal of endocrinological investigation},
  volume={25 3},
Lingual thyroid is the result of a defective migration of the thyroid anlage occurring between the 3rd and 7th week of gestation. Whereas mutations in the transcription factor-2 (TTF-2) and PAX8 and in the TSH receptor genes (TSH-R) have been reported in a minority of patients with thyroid dysgenesis, the etiopathogeny of the majority of cases, and in particular of thyroid ectopy, remains unclear. The majority of patients with thyroid ectopy are asymptomatic, but obstructive symptoms as well as… CONTINUE READING


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