Lingual BDNF and NT-3 mRNA expression patterns and their relation to innervation in the human tongue: similarities and differences compared with rodents.

@article{Nosrat2000LingualBA,
  title={Lingual BDNF and NT-3 mRNA expression patterns and their relation to innervation in the human tongue: similarities and differences compared with rodents.},
  author={Irina Vukmanovic Nosrat and Sven Lindskog and {\AA}ke Seiger and Christopher A. Nosrat},
  journal={The Journal of comparative neurology},
  year={2000},
  volume={417 2},
  pages={133-52}
}
Brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT-3) mRNAs are expressed in developing and adult rodent tongue and are important for the proper development of lingual gustatory and somatosensory innervation in rodents. Here, we wished to determine whether the findings in rodents apply to humans. By using in situ hybridization histochemistry, distinct, specific, and in some instances overlapping patterns of BDNF and NT-3 mRNA expression were found in the developing and adult human… CONTINUE READING

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