Linezolid pharmacokinetics in patients with acute renal failure undergoing continuous venovenous hemodiafiltration.

@article{Carcelero2012LinezolidPI,
  title={Linezolid pharmacokinetics in patients with acute renal failure undergoing continuous venovenous hemodiafiltration.},
  author={Esther Carcelero and Dolors Soy and Laura Guerrero and Esteban Poch and J. Fern{\'a}ndez and Pedro Filipe Martins de Castro and Jos{\'e} Paulo Ribas},
  journal={Journal of clinical pharmacology},
  year={2012},
  volume={52 9},
  pages={1430-5}
}
A renal failure (ARF) is relatively common in the intensive care unit (ICU) setting, and it is associated with an increased mortality (23%-52%). Some patients with ARF will need renal replacement therapy. A high percentage of critically ill patients with ARF do not tolerate intermittent hemodialysis because of hemodynamic instability. Continuous renal replacement therapy (CRRT) runs continuously over a 24-hour period (unlike conventional hemodialysis, which generally lasts about 4 hours and is… CONTINUE READING

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