Linezolid eradicates MRSA better than vancomycin from surgical-site infections.

@article{Weigelt2004LinezolidEM,
  title={Linezolid eradicates MRSA better than vancomycin from surgical-site infections.},
  author={John A Markus Weigelt and Haytham M. A. Kaafarani and Kamal M. F. Itani and Robert N Swanson},
  journal={American journal of surgery},
  year={2004},
  volume={188 6},
  pages={760-6}
}
BACKGROUND The purpose of this analysis was to compare the efficacy of linezolid versus vancomycin in patients with suspected or proven gram-positive methicillin-resistant Staphylococcus aureus (MRSA) surgical-site infections. METHODS An open-label, randomized, comparator-controlled, multicenter, multinational study was conducted in hospitalized patients. Patients were randomized 1:1 to receive linezolid 600 mg (intravenous [IV] or oral) every 12 hours (n = 66) or vancomycin 1 g every 12… CONTINUE READING