• DOI:10.2147/DDDT.S164515
Corpus ID: 49427595

Linezolid: a review of its properties, function, and use in critical care

@article{Hashemian2018LinezolidAR,
  title={Linezolid: a review of its properties, function, and use in critical care},
  author={S. R. Hashemian and T. Farhadi and Mojdeh Ganjparvar},
  journal={Drug Design, Development and Therapy},
  year={2018},
  volume={12},
  pages={1759 - 1767}
}

S. R. Hashemian, T. Farhadi, Mojdeh Ganjparvar

Published 2018

Medicine

Drug Design, Development and Therapy

Linezolid can be considered as the first member of the class of oxazolidinone antibiotics. The compound is a synthetic antibiotic that inhibits bacterial protein synthesis through binding to rRNA. It also inhibits the creation of the initiation complex during protein synthesis which can reduce the length of the developed peptide chains, and decrease the rate of reaction of translation elongation. Linezolid has been approved for the treatment of infections caused by vancomycin-resistant… CONTINUE READING

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