Linezolid: a promising option in the treatment of Gram-positives.

  title={Linezolid: a promising option in the treatment of Gram-positives.},
  author={Abed Zahedi Bialvaei and Mohammad Reza Rahbar and Mehdi Yousefi and Mohammad Asgharzadeh and Hossein Samadi Kafil},
  journal={The Journal of antimicrobial chemotherapy},
  volume={72 2},
Linezolid, an oxazolidinone antimicrobial agent that acts by inhibiting protein synthesis in a unique fashion, is used in the treatment of community-acquired pneumonia, skin and soft-tissue infections and other infections caused by Gram-positive bacteria including VRE and methicillin-resistant staphylococci. Currently, linezolid resistance among these pathogens remains low, commonly <1.0%, although the prevalence of antibiotic resistance is increasing in many countries. Therefore, the… CONTINUE READING