Linear plasmids and chromosomes in bacteria

  title={Linear plasmids and chromosomes in bacteria},
  author={J. Hinnebusch and K. Tilly},
  journal={Molecular Microbiology},
  • J. Hinnebusch, K. Tilly
  • Published 1993
  • Biology, Medicine
  • Molecular Microbiology
  • Linear plasmids and chromosomes were unknown in prokaryotes until recently but have now been found in spirochaetes, Gram‐positive bacteria, and Gram‐negative bacteria. Two structural types of bacterial linear DNA have been characterized. Linear plasmids of the spirochaete Borrelia have a covalently closed hairpin loop at each end and linear plasmids of the Gram‐positive filamentous Streptomyces have a covalently attached protein at each end. Replicons with similar structures are more frequent… CONTINUE READING
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