Linear plasmids and chromosomes in bacteria

@article{Hinnebusch1993LinearPA,
  title={Linear plasmids and chromosomes in bacteria},
  author={Joseph Hinnebusch and Kit Tilly},
  journal={Molecular Microbiology},
  year={1993},
  volume={10}
}
Linear plasmids and chromosomes were unknown in prokaryotes until recently but have now been found in spirochaetes, Gram‐positive bacteria, and Gram‐negative bacteria. Two structural types of bacterial linear DNA have been characterized. Linear plasmids of the spirochaete Borrelia have a covalently closed hairpin loop at each end and linear plasmids of the Gram‐positive filamentous Streptomyces have a covalently attached protein at each end. Replicons with similar structures are more frequent… Expand
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References

SHOWING 1-10 OF 50 REFERENCES
Linear plasmids of the bacterium Borrelia burgdorferi have covalently closed ends.
TLDR
These studies provide direct visual evidence that the linear plasmids have covalently closed ends, which occurs in some animal viruses, but it has not heretofore been described in prokaryotic organisms. Expand
Invertrons, a class of structurally and functionally related genetic elements that includes linear DNA plasmids, transposable elements, and genomes of adeno-type viruses.
TLDR
A model for replication and integration of invertrons is presented, as well as a model for transposition of transposable elements. Expand
Reconstruction of a Streptomyces linear replicon from separately cloned DNA fragments: existence of a cryptic origin of circular replication within the linear plasmid.
  • D. Shiffman, S. Cohen
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1992
TLDR
The reconstruction of a functional linear replicon, the 12-kilobase Streptomyces clavuligerus plasmid pSCL, from separate DNA fragments cloned in Escherichia coli on the pUC19 plasmids is reported, indicating the existence of a cryptic origin of circular replication within the linear plasmide. Expand
A LINEAR PLASMID-LIKE DNA IN STREPTOMYCES SP. PRODUCING LANKACIDIN GROUP ANTIBIOTICS
TLDR
Results suggest that the linear plasmid-like DNA was isolated from a lysate of Streptomyces sp. Expand
Linear plasmids of Borrelia burgdorferi have a telomeric structure and sequence similar to those of a eukaryotic virus
TLDR
Findings suggest that the novel linear plasmids of Borrelia originated through a horizontal genetic transfer across kingdoms. Expand
Characterization of a linear extrachromosomal DNA element (pBL1) isolated after interspecific mating between Streptomyces bambergiensis and S. lividans.
TLDR
After mating with the plasmidless S. lividans strain TK64, conjugants carrying a smaller extrachromosomal DNA element, pBL1, were identified and it was found that the absence of this protein drastically reduces the transforming efficiency of p BL1. Expand
Temperate bacteriophages of Streptococcus pneumoniae that contain protein covalently linked to the 5' ends of their DNA
TLDR
The protein bound to the DNA in the three phages studied, iodinated in vitro with 125I, has a molecular weight of 23,000 as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and treatment of the complexes with chaotropic agents suggested that the protein is covalently bound toThe 5' termini of the DNA. Expand
The conjugative plasmid SLP2 of Streptomyces lividans is a 50 kb linear molecule
TLDR
The SLP2 plasmid, demonstrated genetically to exist In Streptomyces lividans by its ability to promote conjugation and to elicit‘pocks’on recipient (SLP2−) cultures, is physically detected and partially homologous to a newly discovered 650 kb linear plasmids in S. parvulus. Expand
Resolution of linear minichromosomes with hairpin ends from circular plasmids containing vaccinia virus concatemer junctions
TLDR
It is indicated that concatemers can serve as replicative intermediates and account for the generation of flip-flop sequence variation of the hairpins at the ends of the mature vaccinia virus genome. Expand
Complete nucleotide sequence of a linear plasmid from Streptomyces clavuligerus and characterization of its RNA transcripts
  • X. Wu, K. Roy
  • Biology, Medicine
  • Journal of bacteriology
  • 1993
TLDR
The larger of the two RNA species was present at a high level during the early stage of growth in liquid medium, and then its apparent rate of transcription decreased and remained at a lower level through the later stages; the level of the smaller RNA species remained relatively constant through all stages of growth. Expand
...
1
2
3
4
5
...