Linear plasmids and chromosomes in bacteria

@article{Hinnebusch1993LinearPA,
  title={Linear plasmids and chromosomes in bacteria},
  author={J. Hinnebusch and K. Tilly},
  journal={Molecular Microbiology},
  year={1993},
  volume={10}
}
  • J. Hinnebusch, K. Tilly
  • Published 1993
  • Biology, Medicine
  • Molecular Microbiology
  • Linear plasmids and chromosomes were unknown in prokaryotes until recently but have now been found in spirochaetes, Gram‐positive bacteria, and Gram‐negative bacteria. Two structural types of bacterial linear DNA have been characterized. Linear plasmids of the spirochaete Borrelia have a covalently closed hairpin loop at each end and linear plasmids of the Gram‐positive filamentous Streptomyces have a covalently attached protein at each end. Replicons with similar structures are more frequent… CONTINUE READING
    181 Citations

    Topics from this paper

    Prokaryotic and Mitochondrial Linear Genomes: Their Genesis, Evolutionary Significance, and the Problem of Replicating Chromosome Ends
    • Highly Influenced
    Bacterial plasmids: replication of extrachromosomal genetic elements encoding resistance to antimicrobial compounds.
    • 63
    • Highly Influenced
    • PDF
    A new beginning with new ends: linearisation of circular chromosomes during bacterial evolution.
    • 100
    • Highly Influenced
    • PDF
    The Sequence of a 1.8-Mb Bacterial Linear Plasmid Reveals a Rich Evolutionary Reservoir of Secondary Metabolic Pathways
    • 154
    • PDF
    Streptomyces linear plasmids that contain a phage‐like, centrally located, replication origin
    • 50
    The circle is broken: telomere resolution in linear replicons.
    • 51
    • PDF

    References

    SHOWING 1-10 OF 50 REFERENCES
    Reconstruction of a Streptomyces linear replicon from separately cloned DNA fragments: existence of a cryptic origin of circular replication within the linear plasmid.
    • D. Shiffman, S. Cohen
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1992
    • 52
    • PDF