Linear high intensity area along the medial margin of the internal segment of the globus pallidus in Machado-Joseph disease patients.

@article{Yamada2005LinearHI,
  title={Linear high intensity area along the medial margin of the internal segment of the globus pallidus in Machado-Joseph disease patients.},
  author={Shigeo Yamada and Jin Nishimiya and Takashi Nakajima and Fumitoshi Taketazu},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2005},
  volume={76 4},
  pages={573-5}
}
Our new finding on magnetic resonance imaging (MRI) of Machado-Joseph disease (MJD) patients indicates degeneration of the lenticular fasciculus (LF), a major outflow of the internal segment of the globus pallidus (GPi). We examined the clinical, radiological, and autopsy findings of one MJD patient and then retrospectively reviewed the MRI images of another 15 patients looking for a similar abnormal signal intensity. The significance of the clinicoradiological correlation of the MRI finding… CONTINUE READING