Corpus ID: 17873509

Linear Model Predictive Controller for Closed-Loop Control of Intravenous Anesthesia with Time Delay

  title={Linear Model Predictive Controller for Closed-Loop Control of Intravenous Anesthesia with Time Delay},
  author={Deepak D. Ingole and D. Sonawane and V. V. Naik and Divyesh Ginoya and Vedika V. Patki},
  • Deepak D. Ingole, D. Sonawane, +2 authors Vedika V. Patki
  • Published 2013
  • 8 Abstract—During intravenous anesthesia, anesthetic drugs must be administered at a suitable rate to prevent over dosing and under dosing in a patient. A developed PharmacokineticPharmacodynamic (PK/PD) model, which has been used to study the relationship between administered anesthetic dose and its effect on the patient in terms of hypnosis, is considered. In this paper, Linear Model Predictive Controller (LMPC) framework based on Active Set Method (ASM) with modified approach for closed loop… CONTINUE READING
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