Linear IgE epitope mapping of the English walnut (Juglans regia) major food allergen, Jug r 1.

@article{Robotham2002LinearIE,
  title={Linear IgE epitope mapping of the English walnut (Juglans regia) major food allergen, Jug r 1.},
  author={Jason M. Robotham and SuzanneS. Teuber and Shridhar K Sathe and Kenneth H. Roux},
  journal={The Journal of allergy and clinical immunology},
  year={2002},
  volume={109 1},
  pages={
          143-9
        }
}
BACKGROUND Peanut and tree nut allergies can be life-threatening, and they appear to be growing in prevalence. Jug r 1, a 2S albumin seed storage protein, was previously characterized as a major English walnut food allergen. OBJECTIVE We sought to identify the linear IgE-binding epitopes of Jug r 1 and to determine which, if any, amino acids are necessary for this binding to occur. METHODS Pools of sera from walnut-allergic patients and overlapping peptides synthesized on an activated… CONTINUE READING

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