Lineage tracing evidence for in vitro dedifferentiation but rare proliferation of mouse pancreatic beta-cells.

Abstract

Understanding and manipulating pancreatic beta-cell proliferation is a major challenge for pancreas biology and diabetes therapy. Recent studies have raised the possibility that human beta-cells can undergo dedifferentiation and give rise to highly proliferative mesenchymal cells, which retain the potential to redifferentiate into beta-cells. To directly… (More)

Topics

5 Figures and Tables

Cite this paper

@article{Weinberg2007LineageTE, title={Lineage tracing evidence for in vitro dedifferentiation but rare proliferation of mouse pancreatic beta-cells.}, author={Noa Weinberg and Limor Ouziel-Yahalom and Sarah Knoller and Shimon Efrat and Yuval Dor}, journal={Diabetes}, year={2007}, volume={56 5}, pages={1299-304} }