Lineage structures in the genome sequences of three Epstein-Barr virus strains.

@article{McGeoch2007LineageSI,
  title={Lineage structures in the genome sequences of three Epstein-Barr virus strains.},
  author={D. J. McGeoch and Derek Gatherer},
  journal={Virology},
  year={2007},
  volume={359 1},
  pages={1-5}
}
Whole genome sequences for three Epstein-Barr virus strains (B95-8, GD1 and AG876) were aligned and compared. In addition to known variable loci (including type-specific alleles for the EBNA2, EBNA3A, EBNA3B and EBNA3C genes, plus the EBNA1 and LMP1 genes), seven large-scale regions of lower-level diversity were identified with strains at each in two major groupings. All three possible patterns of strain associations were represented across the seven loci. Tree-building studies supported the… CONTINUE READING

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