Lineage mapping identifies molecular and architectural similarities between the larval and adult Drosophila central nervous system.

@article{Lacin2016LineageMI,
  title={Lineage mapping identifies molecular and architectural similarities between the larval and adult Drosophila central nervous system.},
  author={Haluk Lacin and James W. Truman},
  journal={eLife},
  year={2016},
  volume={5},
  pages={e13399}
}
Neurogenesis in Drosophila occurs in two phases, embryonic and post-embryonic, in which the same set of neuroblasts give rise to the distinct larval and adult nervous systems, respectively. Here, we identified the embryonic neuroblast origin of the adult neuronal lineages in the ventral nervous system via lineage-specific GAL4 lines and molecular markers. Our lineage mapping revealed that neurons born late in the embryonic phase show axonal morphology and transcription factor profiles that are… CONTINUE READING
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