Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches.

@article{Pinho2018LineageBiasedHS,
  title={Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches.},
  author={Sandra Pinho and Tony Marchand and Eva Y Yang and Qiaozhi Wei and Claus Nerlov and Paul S Frenette},
  journal={Developmental cell},
  year={2018},
  volume={44 5},
  pages={634-641.e4}
}
The spatial localization of hematopoietic stem cells (HSCs) in the bone marrow (BM) remains controversial, with some studies suggesting that they are maintained in homogeneously distributed niches while others have suggested the contributions of distinct niche structures. Subsets of quiescent HSCs have been reported to associate with megakaryocytes (MK) or… CONTINUE READING