Line-field confocal optical coherence tomography for high-resolution noninvasive imaging of skin tumors

@article{Dubois2018LinefieldCO,
  title={Line-field confocal optical coherence tomography for high-resolution noninvasive imaging of skin tumors},
  author={Arnaud Dubois and Olivier Levecq and Hicham Azimani and David Siret and Ana{\"i}s Barut and Mariano Suppa and V{\'e}ronique del Marmol and Josep Malvehy and Elisa Cinotti and Pietro Rubegni and Jean Luc Perrot},
  journal={Journal of Biomedical Optics},
  year={2018},
  volume={23}
}
Abstract. An optical technique called line-field confocal optical coherence tomography (LC-OCT) is introduced for high-resolution, noninvasive imaging of human skin in vivo. LC-OCT combines the principles of time-domain optical coherence tomography and confocal microscopy with line illumination and detection using a broadband laser and a line-scan camera. LC-OCT measures the echo-time delay and amplitude of light backscattered from cutaneous microstructures through low-coherence interferometry… Expand
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TLDR
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TLDR
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TLDR
An LC-OCT device based on a custom-designed Mirau interferometer that offers similar spatial resolution and detection sensitivity and has the advantage of being more compact and lighter is presented. Expand
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An imaging device based on line-field confocal optical coherence tomography (LC-OCT) operating in two distinct spectral bands centered at 770 nm and 1250 nm is presented. A single supercontinuumExpand
Switchable vertical/horizontal section imaging with line-field confocal optical coherence tomography
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Simultaneous dual-band line-field confocal optical coherence tomography: application to skin imaging.
Line-field confocal optical coherence tomography (LC-OCT) operating in two distinct spectral bands centered at 770 nm and 1250 nm is reported, using a single supercontinuum light source and twoExpand
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References

SHOWING 1-10 OF 69 REFERENCES
Line-field confocal optical coherence tomography
We present an improved time-domain optical coherence tomography technique designed for ultrahigh-resolution B-scan imaging in real-time. The technique, called line-field confocal optical coherenceExpand
Improved Detection Sensitivity of Line-Scanning Optical Coherence Microscopy
TLDR
Improved detection sensitivity is demonstrated by using an achromatic design for line-field generation by line-scanning OCM, a new form of OCM that utilizes line- field illumination for parallel detection. Expand
Optical Coherence Tomography in the Diagnosis of Skin Cancer.
Optical coherence tomography (OCT) has emerged as a novel noninvasive imaging device that allows for the real-time, in vivo, cross-sectional imaging of skin morphology. OCT has increased imagingExpand
Optical coherence tomography of the human skin.
TLDR
OCT is a promising new imaging method for visualization of morphologic changes of superficial layers of the human skin that may be useful for noninvasive diagnosis of bullous skin diseases, skin tumors, and in vivo investigation of pharmacologic effects. Expand
A compact high-speed full-field optical coherence microscope for high-resolution in vivo skin imaging.
TLDR
Images of human skin, revealing in-depth cellular-level structures, were obtained in vivo and in real-time without the need for stabilization of the subject. Expand
Full-Field Optical Coherence Tomography: A New Technology for 3D High-Resolution Skin Imaging
TLDR
Full-field optical coherence tomography is a novel technology in the field of skin imaging that has the potential to be a relevant complement to existing non-invasive imaging modalities for clinical and cosmetic applications. Expand
Optical coherence microscopy for deep tissue imaging of the cerebral cortex with intrinsic contrast
TLDR
Using OCM, it is shown that OCM enables direct visualization of cellular changes during cell depolarization and may therefore provide novel optical markers of cell viability. Expand
High-resolution multiphoton tomography of human skin with subcellular spatial resolution and picosecond time resolution.
TLDR
The novel noninvasive multiphoton autofluorescence-SHG imaging technique provides 4-D (x,y,z,tau) optical biopsies with subcellular resolution and offers the possibility of introducing a high-resolution optical diagnostic method in dermatology. Expand
Gabor-based fusion technique for Optical Coherence Microscopy.
TLDR
The image acquisition enabled by this optical probe when combined with an automatic data fusion method developed and described here to produce an in-focus high resolution image throughout the imaging depth of the sample is reported on. Expand
Optical Coherence Tomography
A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce aExpand
...
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5
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