Lincomycin increases synthetic rate and periplasmic pool size for cholera toxin.

@article{Levner1980LincomycinIS,
  title={Lincomycin increases synthetic rate and periplasmic pool size for cholera toxin.},
  author={Mark H. Levner and C. Urbano and Benjamin Arnold Rubin},
  journal={Journal of bacteriology},
  year={1980},
  volume={143 1},
  pages={441-7}
}
Increased enterotoxigenicity of Vibrio cholerae 569B grown with low concentrations of lincomycin, previously described in terms of increased extracellular biological activity (capillary permeability factor and fluid accumulation in ligated rabbit ileal loops), was further characterized. Polyacrylamide gel electrophoresis and single radial immunodiffusion showed that lincomycin-stimulated cells produced increased molar quantities of cholera toxin (CT) both extra- and intracellularly. The… CONTINUE READING