Linaclotide: A new drug for the treatment of chronic constipation and irritable bowel syndrome with constipation.

@article{Corsetti2013LinaclotideAN,
  title={Linaclotide: A new drug for the treatment of chronic constipation and irritable bowel syndrome with constipation.},
  author={Maura Corsetti and Jan Tack},
  journal={United European gastroenterology journal},
  year={2013},
  volume={1 1},
  pages={7-20}
}
INTRODUCTION Linaclotide is the first member of a novel class of drugs to be extensively evaluated for the treatment of chronic constipation (CC) and irritable bowel syndrome with constipation (IBS-C). AIM To provide a comprehensive overview of the current state of knowledge on linaclotide, its pharmacological properties, mode of action and efficacy in clinical trials to date. METHODS We conducted a systematic review of the literature. RESULTS The survey revealed that linaclotide is a… CONTINUE READING
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