Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells.

@article{Kim2013LimonoidsAT,
  title={Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells.},
  author={Jinhee Kim and Guddadarangavvanahally K Jayaprakasha and Bhimanagouda S Patil},
  journal={Food & function},
  year={2013},
  volume={4 2},
  pages={258-65}
}
Lemons are a widely used citrus crop and have shown several potential health benefits. In the present study, the mechanism and effectiveness of the anti-cancer and anti-aromatase properties of limonoids were investigated for the first time. Defatted lemon (Citrus lemon L. Burm) seed powder was extracted with ethyl acetate (EtOAc) and methanol (MeOH) for 16 h each, successively. These extracts were fractionated using 1D (silica) and 2D (ion exchange and SP-70 columns) column chromatography to… CONTINUE READING
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