Limonene-induced regression of mammary carcinomas.

  title={Limonene-induced regression of mammary carcinomas.},
  author={Jill D. Haag and Mary J. Lindstrom and Michael N. Gould},
  journal={Cancer research},
  volume={52 14},
Dietary administration of the monocyclic monoterpenoid d-limonene causes complete regression of both dimethylbenz[alpha]anthracene- and N-nitroso-N-methylurea-induced rat mammary carcinomas. Carcinomas regress when limonene is added to the diet either when the tumor is small and still capable of spontaneously regressing or when it is large and progressed beyond the stage when it is susceptible to spontaneous regression. The limonene dose-tumor regression response relationship is steep… CONTINUE READING