Limits to the temporal fidelity of cortical spike rate signals

  title={Limits to the temporal fidelity of cortical spike rate signals},
  author={Mark E. Mazurek and Michael N. Shadlen},
  journal={Nature Neuroscience},
The cerebral cortex processes information primarily through changes in the spike rates of neurons within local ensembles. To evaluate how reliably the average spike rate of a group of cortical neurons can represent a time-varying signal, we simulated an ensemble with realistic spike discharge behavior. We found that weak interneuronal correlation, or synchrony, allows the variability in spike rates of individual neurons to compromise the ensemble representation of time-varying signals. Brief… CONTINUE READING