Limits to the capacity of transplants of olfactory glia to promote axonal regrowth in the CNS.

@article{GudioCabrera2000LimitsTT,
  title={Limits to the capacity of transplants of olfactory glia to promote axonal regrowth in the CNS.},
  author={Graciela Gudi{\~n}o-Cabrera and Angel M Pastor and Rosa R de la Cruz and J. M. Delgado-Garc{\'i}a and Manuel Nieto-Sampedro},
  journal={Neuroreport},
  year={2000},
  volume={11 3},
  pages={467-71}
}
Olfactory bulb ensheathing cell (OBEC) transplants promoted axonal regeneration in the spinal cord dorsal root entry zone and in the corticospinal tract. However, OBECs failed to promote abducens internuclear neuron axon regeneration when transplanted at the site of nerve fibre transection. In experiments performed in both cats and rats, OBECs survived for up to 2 months, lining themselves up along the portion of the regrowing axons proximal to the interneuron cell body. However, OBECs migrated… CONTINUE READING

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