Limiting iron supplementation for anemia in dialysis patients--the Basis for Japan's conservative guidelines.

@article{Yamamoto2011LimitingIS,
  title={Limiting iron supplementation for anemia in dialysis patients--the Basis for Japan's conservative guidelines.},
  author={Hiroyasu Yamamoto and Yoshiharu Tsubakihara},
  journal={Seminars in dialysis},
  year={2011},
  volume={24 3},
  pages={269-71}
}
Both the Kidney Disease Outcomes Quality Initiative (KDOQI) Guidelines and the European Best Practice Guidelines (EBPG) support the use of substantial doses of iron supplementation when iron overload cannot be confirmed. However, excessive iron reduces iron utilization and is involved in the generation of intracellular reactive oxygen species, which induce cell injury; the risk of subtle toxicity from iron excess exists. Unnecessary iron supplementation also accelerates hepcidin (HP) production… CONTINUE READING

Similar Papers

Loading similar papers…