Limiting dilution assays. Experimental design and statistical analysis.

@article{Strijbosch1987LimitingDA,
  title={Limiting dilution assays. Experimental design and statistical analysis.},
  author={Leo W. G. Strijbosch and Wim A. Buurman and Ronald J. M. M. Does and P H Zinken and G. L. M. Groenewegen},
  journal={Journal of immunological methods},
  year={1987},
  volume={97 1},
  pages={
          133-40
        }
}
Two issues in limiting dilution analysis are considered. The first concerns the experimental design: a mathematical algorithm has been developed which calculates the number of replicate culture groups, and the (mean) number of cells per well to be used on the basis of the experimenter's a priori information about the unknown frequency. The procedure guarantees useful data if the a priori interval estimate of the frequency to be determined is correct and the cells are willing to grow. The second… CONTINUE READING
BETA

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 54 CITATIONS

FILTER CITATIONS BY YEAR

1988
2019

CITATION STATISTICS

  • 3 Highly Influenced Citations

  • 100% Increase in citations per year in 2018 over 2017

Similar Papers

Loading similar papers…