Limited regression of central giant cell granuloma by interferon alpha after failed calcitonin therapy: a report of 2 cases.

@article{Lange2006LimitedRO,
  title={Limited regression of central giant cell granuloma by interferon alpha after failed calcitonin therapy: a report of 2 cases.},
  author={J de de Lange and Hans P van den Akker and Henk van den Berg and Dirk J Richel and Richmond Gortzak},
  journal={International journal of oral and maxillofacial surgery},
  year={2006},
  volume={35 9},
  pages={865-9}
}
Central giant cell granuloma (CGCG) is a benign lesion of the jaws with a sometimes locally aggressive behaviour. The most common therapy is surgical curettage which has a high recurrence rate, especially in lesions with aggressive signs and symptoms (i.e. pain, paresthesia, root-resorption and rapid growth). Alternative therapies such as interferon alpha (INFalpha) or calcitonin are described in the literature. In this study 2 patients with an aggressive CGCG are presented who were treated… CONTINUE READING

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