Limited proteolysis of MP26 in lens fiber plasma membranes of the galactose-induced cataract in the rat.

@article{Alcala1986LimitedPO,
  title={Limited proteolysis of MP26 in lens fiber plasma membranes of the galactose-induced cataract in the rat.},
  author={Julian Alcala and Nalin J. Unakar and Malkhan Katar and J. L. Y. Tsui},
  journal={Current eye research},
  year={1986},
  volume={5 9},
  pages={697-703}
}
Lenses of rats maintained on a 50% galactose diet displayed the development of a progressive cataract which was cortical at 3-11 days, and progressively internalized (nuclear as well) and mature at 16-20 days of feeding. Lens fiber plasma membranes were isolated from female rats subjected to the galactose diet and from controls at 11, 19, and 31 days of feeding, and analyzed by SDS-PAGE. Examination of the fiber plasma membranes from whole lenses of galactose-fed rats demonstrated the limited… CONTINUE READING