Limited prognostic value of preoperative circulating tumor cells for early biochemical recurrence in patients with localized prostate cancer.

@article{Meyer2016LimitedPV,
  title={Limited prognostic value of preoperative circulating tumor cells for early biochemical recurrence in patients with localized prostate cancer.},
  author={Christian P. Meyer and Klaus Pantel and Pierre Tennstedt and Petra Stroelin and Thorsten Schlomm and Hans Heinzer and Sabine Riethdorf and Thomas Steuber},
  journal={Urologic oncology},
  year={2016},
  volume={34 5},
  pages={235.e11-6}
}
INTRODUCTION The presence of circulating tumor cells (CTCs) is an established marker for prognosis in men with castration-resistant prostate cancer. A cutoff of ≥5 CTCs/7.5ml blood in the CellSearch Epithelial Cell Test has been shown to stratify prognostic groups and predict outcome of abiraterone treatment. In contrast, the value of CTC detection in men with localized prostrate cancer before radical prostatectomy (RP) is unknown. MATERIALS AND METHODS A total of 152 patients treated with RP… CONTINUE READING