Limited evidence for classic selective sweeps in African populations.

@article{Granka2012LimitedEF,
  title={Limited evidence for classic selective sweeps in African populations.},
  author={Julie M. Granka and Brenna M Henn and Christopher R Gignoux and Jeffrey M. Kidd and Carlos Daniel Bustamante and Marcus W. Feldman},
  journal={Genetics},
  year={2012},
  volume={192 3},
  pages={1049-64}
}
While hundreds of loci have been identified as reflecting strong-positive selection in human populations, connections between candidate loci and specific selective pressures often remain obscure. This study investigates broader patterns of selection in African populations, which are underrepresented despite their potential to offer key insights into human adaptation. We scan for hard selective sweeps using several haplotype and allele-frequency statistics with a data set of nearly 500,000… CONTINUE READING
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