Limited anxiolytic-like effects of non-benzodiazepine hypnotics in rodents

  title={Limited anxiolytic-like effects of non-benzodiazepine hypnotics in rodents},
  author={G. Griebel and G. Perrault and D. Sanger},
  journal={Journal of Psychopharmacology},
  pages={356 - 365}
  • G. Griebel, G. Perrault, D. Sanger
  • Published 1998
  • Medicine, Psychology
  • Journal of Psychopharmacology
  • The present experiments compared the anxiolytic-like effects of the benzodiazepine (BZD) hypnotic triazolam with those of four non-BZD hypnotics including one non-selective (zopiclone) and three ω1-BZD selective (zolpidem, zaleplon and SX-3228) receptor ligands, in classical animal models including conflict tests (punished lever pressing and punished drinking tests in rats) and exploratory models (elevated plus-maze test in rats and light/dark choice test in mice), and a recently developed… CONTINUE READING
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