Limited and localized outbreak of newly emergent type 2 vaccine-derived poliovirus in Sichuan, China.

@article{Yan2014LimitedAL,
  title={Limited and localized outbreak of newly emergent type 2 vaccine-derived poliovirus in Sichuan, China.},
  author={Dongmei Yan and Yong Zhang and Shuang-li Zhu and Na Chen and Xiaolei Li and Dongyan Wang and Xiaozhen Ma and Hongbo Jin and Wenbin Tong and Wenbo Xu},
  journal={Clinical and vaccine immunology : CVI},
  year={2014},
  volume={21 7},
  pages={1012-8}
}
From August 2011 to February 2012, an outbreak caused by type 2 circulating vaccine-derived poliovirus (cVDPV) occurred in Aba County, Sichuan, China. During the outbreak, four type 2 VDPVs (≥0.6% nucleotide divergence in the VP1 region relative to the Sabin 2 strain) were isolated from 3 patients with acute flaccid paralysis (AFP) and one close contact. In addition, a type 2 pre-VDPV (0.3% to 0.5% divergence from Sabin 2) that was genetically related to these type 2 VDPVs was isolated from… CONTINUE READING
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