Limited Left Ventricular Response to Volume Overload in the Neonatal Period: a Comparative Study with the Adult Animal

@article{Romero1979LimitedLV,
  title={Limited Left Ventricular Response to Volume Overload in the Neonatal Period: a Comparative Study with the Adult Animal},
  author={Tom{\'a}s e Romero and William F. Friedman},
  journal={Pediatric Research},
  year={1979},
  volume={13},
  pages={910-915}
}
Summary: The unique fragility of the neonatal circulation in response to disease states and various physiologic stimuli is apparent clinically, although underlying mechanisms have not been explored. Accordingly, this report examines and compares the influence on cardiac performance of changes in left ventricular (LV) filling pressure in six conscious, unscdated newborn lambs studied serially at 1 and 3 weeks of age and five adult sheep. All animals were instrumented chronically to assess LV… CONTINUE READING
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