Limited Endothelial Plasticity of Mesenchymal Stem Cells Revealed by Quantitative Phenotypic Comparisons to Representative Endothelial Cell Controls

@inproceedings{Antonyshyn2019LimitedEP,
  title={Limited Endothelial Plasticity of Mesenchymal Stem Cells Revealed by Quantitative Phenotypic Comparisons to Representative Endothelial Cell Controls},
  author={Jeremy A Antonyshyn and Meghan J McFadden and Anthony O Gramolini and Stefan O P Hofer and J Paul Santerre},
  booktitle={Stem cells translational medicine},
  year={2019}
}
Considerable effort has been directed toward deriving endothelial cells (ECs) from adipose-derived mesenchymal stem cells (ASCs) since 2004, when it was first suggested that ECs and adipocytes share a common progenitor. While the capacity of ASCs to express endothelial markers has been repeatedly demonstrated, none constitute conclusive evidence of an endothelial phenotype as all reported markers have been detected in other, non-endothelial cell types. In this study, quantitative phenotypic… CONTINUE READING
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