Limitation of glycolysis by hexokinase in rat brain synaptosomes during intense ion pumping.

@article{Ereciska1996LimitationOG,
  title={Limitation of glycolysis by hexokinase in rat brain synaptosomes during intense ion pumping.},
  author={Maria Erecińska and Dominic Nelson and Joseph Deas and Ian A. Silver},
  journal={Brain research},
  year={1996},
  volume={726 1-2},
  pages={153-9}
}
Incubation of rat brain synaptosomes under conditions of either increased energy utilization (addition of Na+ channel opener, veratridine, or ionophores, monensin and nigericin) or inhibition of oxidative phosphorylation (addition of rotenone), or a combination thereof, decreased [ATP], increased [ADP] and stimulated glycolysis. The rates of lactate… CONTINUE READING