Limitation of cardiac output by total isovolumic time during pharmacologic stress in patients with dilated cardiomyopathy: activation-mediated effects of left bundle branch block and coronary artery disease.

@article{Duncan2003LimitationOC,
  title={Limitation of cardiac output by total isovolumic time during pharmacologic stress in patients with dilated cardiomyopathy: activation-mediated effects of left bundle branch block and coronary artery disease.},
  author={Alison M. Duncan and Darrel P. Francis and Michael y. Henein and Derek G. Gibson},
  journal={Journal of the American College of Cardiology},
  year={2003},
  volume={41 1},
  pages={121-8}
}
OBJECTIVES We sought to separate the effects of associated left bundle branch block (LBBB) and coronary artery disease (CAD) on peak cardiac output (CO) during dobutamine stress in patients with dilated cardiomyopathy (DCM). BACKGROUND The mechanisms limiting CO during stress in patients with DCM are unclear. Both LBBB and CAD may do so by prolonging the total isovolumic time (t-IVT). METHODS A total of 59 patients with DCM-34 with CAD (20 normal activation [NA], 14 LBBB) and 25 without CAD… CONTINUE READING

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Left Bundle Branch Block Negatively Affects Coronary Flow Velocity Reserve and Myocardial Contractile Reserve in Nonischemic Dilated Cardiomyopathy.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography • 2016
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