Limbic white matter microstructure plasticity reflects recovery from depression.

  title={Limbic white matter microstructure plasticity reflects recovery from depression.},
  author={Tobias Bracht and Derek K. Jones and Thomas J{\"o}rg M{\"u}ller and Roland Wiest and Sebastian Walther},
  journal={Journal of affective disorders},
BACKGROUND White matter microstructure alterations of limbic and reward pathways have been reported repeatedly for depressive episodes in major depressive disorder (MDD) and bipolar disorder (BD). However, findings during remission are equivocal. It was the aim of this study to investigate if white matter microstructure changes during the time course of clinical remission. METHODS Fifteen depressed patients (11 MDD, 4 BD) underwent diffusion-weighted MRI both during depression, and during… CONTINUE READING
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